Epigenetics Consortium at the University of Minnesota

The Epigenetics Consortium aims to strengthen the epigenetics research at the University of Minnesota and establish us as a major key player in this important field.

Epigenetics is important for many areas of scientific inquiry, including neuroscience, cell development, psychology, epidemiology, cancer, and pharmacology.

Epigenetic Consortium Research

In the flow of genetic information from the genome to the transcriptome, epigenetic regulation plays a critical role in modulating the expression of genotypes to phenotypes in a tissue specific and temporarily specific manner. Epigenetic regulation can take place in the methylation of DNA, covalent modifications of histone, or interactions between nucleosome and DNA.

DNA methylation is the most stable form of epigenetic modification that leads to transcriptional silencing, X chromosome inactivation and imprinting.
Obtaining genome-scale patterns of DNA methylation in different normal and disease tissues are critical for understanding the developmental processes as well as the etiology of many pathologic states including autism and cancer.


1/6/2020 - The Epigenetics Consortium is featured in an article "Your Genes Don't Have to Determine Your Future" by Gao Vang from the Office of Academic Clinical Affairs. 

Upcoming Seminar

Google calendar

Join Us!  Monthly Seminars, All Are Welcome!


March 19, 2020

Rm 105, 717 Delaware Street @ 3:00pm
David Largaespada, PhD
Dept. Pediatrics
University of Minnesota


"Exploiting Synthetic Vulnerabilities from Loss of an Epigenetic Writer in Malignant Peripheral Nerve Sheath Tumors"