Epigenetics Consortium at the University of Minnesota

The Epigenetics Consortium aims to strengthen the epigenetics research at the University of Minnesota and establish us as a major key player in this important field.

Epigenetics is important for many areas of scientific inquiry, including neuroscience, cell development, psychology, epidemiology, cancer, and pharmacology.

Epigenetic Consortium Research

In the flow of genetic information from the genome to the transcriptome, epigenetic regulation plays a critical role in modulating the expression of genotypes to phenotypes in a tissue specific and temporarily specific manner. Epigenetic regulation can take place in the methylation of DNA, covalent modifications of histone, or interactions between nucleosome and DNA.

DNA methylation is the most stable form of epigenetic modification that leads to transcriptional silencing, X chromosome inactivation and imprinting.
 
Obtaining genome-scale patterns of DNA methylation in different normal and disease tissues are critical for understanding the developmental processes as well as the etiology of many pathologic states including autism and cancer.

Upcoming Seminar

Google calendar

Join Us!  Monthly Seminars, All Are Welcome!

 

August 15, 2019

Mayo Clinic Epigenomics Interest Group Seminar

Videoconferencing from 1-101 Microbiology Research Facility @ 12:00pm
 
Yue Chen, PhD
Assistant Professor
Dept. Biochemistry, Molecular Biology, and Biophysics
University of Minnesota
 
“Characterization of Oxygen-dependent Postranslational Modifications with Quantitative Proteomics”